Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(5S)-3-[4-[(E)-(4-[[(4R)-4-hydroxy-4-[(2R,5R)-5-[(1R)-1-hydroxytridecyl]tetrahydrofuran-2-yl]butyl]oxy]phenyl)diazenyl]benzyl]-5-methylfuran-2(5H)-one | - |
Bos taurus | |
(5S)-3-[4-[(E)-(4-[[(7R)-7-hydroxy-7-[(2R,5R)-5-[(1R)-1-hydroxytridecyl]tetrahydrofuran-2-yl]heptyl]oxy]phenyl)diazenyl]benzyl]-5-methylfuran-2(5H)-one | - |
Bos taurus | |
(5S)-3-[4-[(Z)-(4-[[(4R)-4-hydroxy-4-[(2R,5R)-5-[(1R)-1-hydroxytridecyl]tetrahydrofuran-2-yl]butyl]oxy]phenyl)diazenyl]benzyl]-5-methylfuran-2(5H)-one | - |
Bos taurus | |
(5S)-3-[4-[(Z)-(4-[[(7R)-7-hydroxy-7-[(2R,5R)-5-[(1R)-1-hydroxytridecyl]tetrahydrofuran-2-yl]heptyl]oxy]phenyl)diazenyl]benzyl]-5-methylfuran-2(5H)-one | - |
Bos taurus | |
bis-tetrahydrofuran acetogenin | the additional methylenes enhance the hydrophobicity of the spacer region, which may be thermodynamically advantageous for bringing the polar gamma-lactone ring into the membrane-embedded segment of complex I | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bos taurus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + H+ + ubiquinone | Bos taurus | - |
NAD+ + ubiquinol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | complex I also shows NADH oxidase activity | Bos taurus | ? | - |
? | |
NADH + H+ + ubiquinone | - |
Bos taurus | NAD+ + ubiquinol | - |
? | |
NADH + H+ + ubiquinone-1 | - |
Bos taurus | NAD+ + ubiquinol-1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
complex I | - |
Bos taurus |
NADH-ubiquinone oxidoreductase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Bos taurus |